Boehringer Ingelheim acquires Nerio Therapeutics for $1.3bn
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Boehringer Ingelheim has acquired drug discovery and development company Nerio Therapeutics in a $1.3bn deal. Nerio’s small molecules inhibit the protein tyrosine phosphatases N1 and N2 (PTPN1 and PTPN2), which act as immune checkpoints. Through this mechanism, PTPN1/2 inhibition can activate the immune system to fight cancer cells.
Immune checkpoint blockade with current checkpoint inhibitors has transformed the cancer treatment landscape. However, while this approach works for some patients, it does not provide a therapeutic benefit for all. Boehringer Ingelheim is committed to changing this paradigm and extending the benefits of immuno-oncology to more cancer patients with a comprehensive portfolio of therapies based on immune checkpoint blockade to boost the immune system and direct it toward cancer cells.
“Securing the rights to Nerio Therapeutics’ novel checkpoint inhibitors creates a broad panel of exciting new cancer treatment combination opportunities. This brings us a major step closer to our vision of transforming the lives of people living with cancer,” said Paola Casarosa, Member of the Board of Managing Directors at Boehringer Ingelheim with responsibility for the Innovation Unit.
Sanford Madigan, partner at Avalon Bio Ventures, L.P. and co-founder and CEO of Nerio Therapeutics, shares this excitement stating, “We believe Nerio’s small molecule PTPN1/N2 inhibitors have superior drug-like properties and provide a first-in-class opportunity. We are excited to expand Boehringer Ingelheim’s pipeline and commend their commitment to unlock the full potential of our compounds and their mechanistically unique approach to fighting cancer.”
This acquisition is a bold step toward transforming cancer care. It further strengthens Boehringer Ingelheim’s oncology pipeline of cancer cell-directed and immuno-oncology investigational therapies for smart combinations that may offer the greatest benefit for people living with cancer.
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